What Causes Bleeding on HRT in Perimenopause? | PYHP 157

May 05, 2025 00:21:21
What Causes Bleeding on HRT in Perimenopause? | PYHP 157
Progress Your Health Podcast
What Causes Bleeding on HRT in Perimenopause? | PYHP 157

May 05 2025 | 00:21:21

/

Show Notes

In this episode, we address a question from "Victoria" (name changed for privacy), who is experiencing prolonged bleeding while undergoing hormone replacement therapy (HRT). Victoria is in perimenopause and is taking compounded T4/T3 thyroid medication and progesterone. Despite normal test results, she often has bleeding that lasts up to 14 days, and her menstrual cycles are becoming shorter. These symptoms are quite common during perimenopause or when HRT is not properly balanced. Additionally, Victoria is dealing with joint pain and inflammation and wonders if these issues could be related to her hormones.


Topics Discussed:

 

Victoria’s Question:

"Hi! Your podcast is awesome, thanks for making it available! I turned 50 four months ago. Still menstruating monthly - every 27-28 days (with one exception - see below). Generally feeling good - no hot flashes or night sweats that I can tell, sleeping 7-9 hours a night (might wake up once or twice on occasion but generally able to go back to sleep quickly). My brain is working fairly well and my mood is good. No vaginal dryness or libido issues so far. For reference, my mum had her very last period four months after she turned 54, and she has never ever had hot flashes (in case that's useful). For the last two years I have been taking 100mg bio-identical progesterone from day 14 (sometimes I might start it on day 12 or 13 of my cycle if I feel PMS-like symptoms). I have also been taking 1,5 grain compounded thyroid for the last two years. I can honestly say the progesterone and the thyroid medication saved me from a lot of suffering I had started to experience 6 months before I started taking them: I had just turned 48 and I started to gain weight, couldn't sleep, felt depressed and brain-fogged. After starting the progesterone capsule and the compounded thyroid medication I gradually returned to feeling normal again. Lately I have even managed to lose some of the weight I put on. My issues right now: My period, although still regular, is characterized by long bleeding. I can easily bleed for up to 14 days. Granted, the bleeding will lighten up after day 5 or 6 but it will continue for at least as many days, albeit light. And to cap it all, this month I finished bleeding on day 14 and started bleeding again on day 19 (this is the first time my cycle is that short for as long as I can remember). I do yearly vaginal ultrasound - all normal. My last one was in June this year. Questions: Could I manage the bleeding by starting the progesterone earlier in my cycle? If so, on which day? Or do I need to start adding a bit of biest into my regiment? My doctor suggested that I could introduce 2.5mg biest (80/20 ratio) from day 5 to day 25 of my cycle, but I am unclear on how this could solve the bleeding issues. Lastly, I am experiencing some joint pain and joint inflammation lately, and I keep reading that this could be a (peri)menopausal symptom. Could adding a bit of biest help the joint pain? Oh, my skin is also drying up and sometimes breaking out a bit, and I guess that's also related to the change of hormones. It's the bleeding and the joint paint though that I am mostly bothered about. I already have low iron levels as it is, and it's very hard to keep on top of them with the amount of blood I am losing each month. So your input on that matter is greatly appreciated! I eat a reasonable diet (low carb, nothing processed), fast for 16 hours and exercise reasonably (definitely not killing myself at the gym), so I think that's all helping. And I don't have much stress in my life, so THAT is super helpful, too :) Anyway, hope you have all the info needed. Look forward to answers. Thanks very much!"

 

Join us as we delve into these topics to provide insights and potential solutions for women experiencing similar challenges during perimenopause.


If you have a question, please visit our website and click Ask the Doctor a question.

 

Want more insights like this? 

Be sure to subscribe to our newsletter for hormone Q&As, educational guides, and real-world strategies to help you feel like yourself again—especially during perimenopause and menopause.

Join the Progress Your Health Newsletter

 

Stay Connected

 

Disclaimer: All content in this blog, including text, images, audio, video, or other formats, was created for informational purposes only. This video, website, and blog aim to promote consumer/public understanding and general knowledge of various health topics. This content is not a substitute for professional medical advice, diagnosis, or treatment. Please consult your healthcare provider with any questions or concerns you may have regarding your condition before undertaking a new healthcare regimen. Never disregard professional medical advice or delay seeking it because of something you have read on this website. If your healthcare provider is not interested in discussing your health concerns regarding this topic, then it is time to find a new doctor.

Other Episodes

Episode

June 26, 2019
Episode Cover

Perimenopause vs Menopause | PYHP 057

  It is common to mistake perimenopause for menopause and vice versa.  Labs can be misleading. Doctors can be misleading in your concerns about whether...

Listen

Episode

December 18, 2017
Episode Cover

What Causes Heavy Periods? | PYHP 023

You know you have heavy periods when . When you have tampons everywhere. In every single purse, the glove box of your car. In...

Listen

Episode

April 15, 2020
Episode Cover

What Are The Side Effects of Biest? | PYHP 082

Staci’s Question:  Hello, Dr. D, I was on Biest, 80:20 ratio. One mg/mL. I take one click, which is a quarter gram per day....

Listen