Rhythmic Dosing Explained | Estradiol & Progesterone Daily Schedule for Perimenopause & Menopause | PYHP 189

In this episode, Dr. Valorie Davidson and Dr. Robert Maki break down exactly how Dr. Valorie runs her personal rhythmic dosing—including the day-by-day estradiol (E2) and progesterone (P4) schedule that recreates a 28-day ovarian cycle. If you’ve heard us talk about “In-Betweeners” (women transitioning from late perimenopause into early menopause) and wondered how rhythmic dosing actually works in real life, this walkthrough is for you. What you’ll learn ● The difference between static vs rhythmic HRT—and why some In-Betweeners thrive on a cyclical protocol ● How a day-12 estradiol surge (with a softer “landing” on day 13) can mimic physiology